Title : Expression of osteopontin in gentamicin-induced acute tubular necrosis and its recovery process.

Pub. Date : 2001 Mar

PMID : 11231351






3 Functional Relationships(s)
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Protein Name
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1 Expression of osteopontin in gentamicin-induced acute tubular necrosis and its recovery process. Gentamicins secreted phosphoprotein 1 Rattus norvegicus
2 There is little information on the expression and role of OPN in gentamicin-induced acute tubular necrosis (ATN) and its recovery process. Gentamicins secreted phosphoprotein 1 Rattus norvegicus
3 RESULTS: In the gentamicin group, OPN mRNA and protein were expressed in only the PCNA-positive proliferating cortical distal tubules, not in the necrotic proximal tubules, until day 6 after the first administration, but were found markedly in PCNA-positive regenerative proximal and distal tubules on days 10, 15, and 30. Gentamicins secreted phosphoprotein 1 Rattus norvegicus