Title : Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system.

Pub. Date : 2001 Feb 6

PMID : 11231159






1 Functional Relationships(s)
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1 However, addition of antibodies to RCC1 and RanGAP1 shows that Ran-GDP must be converted to Ran-GTP by RCC1 before precursor vesicles are recruited, whereas GTP hydrolysis by Ran stimulated by RanGAP1 promotes vesicle recruitment and is necessary for vesicle fusion to form an intact envelope. Guanosine Triphosphate Ran GTPase activating protein 1 Homo sapiens