Pub. Date : 2001 Mar
PMID : 11222876
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites. | Reactive Oxygen Species | pyruvate carboxylase | Homo sapiens |
| 2 | We hypothesized that reactive oxygen species (ROS) are produced by redox reactions of PCB metabolites. | Reactive Oxygen Species | pyruvate carboxylase | Homo sapiens |
| 3 | We hypothesized that reactive oxygen species (ROS) are produced by redox reactions of PCB metabolites. | Reactive Oxygen Species | pyruvate carboxylase | Homo sapiens |
| 4 | We conclude that dihydroxylated PCBs, and PCB quinones after reaction with GSH, produce superoxide and other ROS both in vitro and in HL-60 cells, and oxidative DNA damage in the form of DNA strand breaks in vitro. | Reactive Oxygen Species | pyruvate carboxylase | Homo sapiens |