Title : The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway.

Pub. Date : 2001 Feb

PMID : 11208021






9 Functional Relationships(s)
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Protein Name
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1 The ABI1 and ABI2 protein phosphatases 2C act in a negative feedback regulatory loop of the abscisic acid signalling pathway. Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
2 These genes have been originally identified by the dominant mutations abi1--1 and abi2--1, which reduce the plant"s responsiveness to the hormone abscisic acid (ABA). Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
3 These genes have been originally identified by the dominant mutations abi1--1 and abi2--1, which reduce the plant"s responsiveness to the hormone abscisic acid (ABA). Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
4 Abi2--1R1 plants displayed a wild-type ABA sensitivity. Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
5 However, doubly mutant plants combining the abi2--1R1 allele and a loss-of-function allele at the ABI1 locus were more responsive to ABA than each of the parental single mutants. Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
6 These data indicate that the wild-type ABI2 phosphatase is a negative regulator of ABA signalling, and that the ABI1 and ABI2 phosphatases have overlapping roles in controlling ABA action. Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
7 These data indicate that the wild-type ABI2 phosphatase is a negative regulator of ABA signalling, and that the ABI1 and ABI2 phosphatases have overlapping roles in controlling ABA action. Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
8 Measurements of PP2C activity in plant extracts showed that the phosphatase activity of ABI1 and ABI2 increases in response to ABA. Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana
9 These results suggest that ABI1 and ABI2 act in a negative feedback regulatory loop of the ABA signalling pathway. Abscisic Acid Protein phosphatase 2C family protein Arabidopsis thaliana