Pub. Date : 2000 Dec
PMID : 11191881
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds. | organophosphorus | paraoxonase 1 | Mus musculus |
| 2 | Human paraoxonase (PON1) is a polymorphic, high-density lipoprotein (HDL)-associated esterase that hydrolyzes the toxic metabolites of several organophosphorus (OP) insecticides and nerve agents. | organophosphorus | paraoxonase 1 | Mus musculus |
| 3 | In the present study, we investigated the in-vivo function of PON1 for detoxifying organophosphorus insecticides in PON1-knockout mice that were challenged via dermal exposure with diazoxon, diazinon and paraoxon. | organophosphorus | paraoxonase 1 | Mus musculus |