Pub. Date : 2001 Jan 30
PMID : 11170409
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Complex gangliosides as cell surface inhibitors for the ecto-NAD+ glycohydrolase of CD38. | Gangliosides | CD38 molecule | Homo sapiens |
| 2 | In the present study, we examined the effect of exogenous gangliosides on the NADase activity of CD38 on the surface of retinoic acid-treated human leukemic HL60 cells and CD38-transfected THP-1 cells. | Gangliosides | CD38 molecule | Homo sapiens |
| 3 | These results suggest a novel role of complex gangliosides for the first time as cell surface inhibitors of CD38 through specific and cis interaction between the oligosaccharide moiety and the extracellular domain. | Gangliosides | CD38 molecule | Homo sapiens |