Title : Transforming growth factor beta inhibits steroidogenic acute regulatory (StAR) protein expression in human ovarian thecal cells.

Pub. Date : 2000 Dec 22

PMID : 11162896






3 Functional Relationships(s)
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1 Cells were also treated with different concentration of TGFbeta1 in the presence of forskolin, combined steroid production was measured at the end of 48 h and after 3 h incubation with 22R-hydroxycholesterol. Steroids transforming growth factor beta 1 Homo sapiens
2 Inhibition in combined steroid production was apparent at the highest concentration of TGFbeta1 tested. Steroids transforming growth factor beta 1 Homo sapiens
3 These results suggest that the effect of TGFbeta1 on steroid production and possibly follicular development may be in part due to its effects on StAR expression. Steroids transforming growth factor beta 1 Homo sapiens