Title : cAMP mediated upregulation of CYP2A5 in mouse hepatocytes.

Pub. Date : 2001 Jan 26

PMID : 11162586






4 Functional Relationships(s)
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Protein Name
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1 Phenobarbital (PB) elicited a 3-fold increase in CYP2A5 expression (catalytic activity and mRNA), while the cAMP and protein kinase A (PKA) stimulators dibutyryl-cAMP, forskolin and Sp-cAMPs caused up to 18-fold increases in the amount of CYP2A5 mRNA. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
2 Phenobarbital (PB) elicited a 3-fold increase in CYP2A5 expression (catalytic activity and mRNA), while the cAMP and protein kinase A (PKA) stimulators dibutyryl-cAMP, forskolin and Sp-cAMPs caused up to 18-fold increases in the amount of CYP2A5 mRNA. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
3 Phenobarbital (PB) elicited a 3-fold increase in CYP2A5 expression (catalytic activity and mRNA), while the cAMP and protein kinase A (PKA) stimulators dibutyryl-cAMP, forskolin and Sp-cAMPs caused up to 18-fold increases in the amount of CYP2A5 mRNA. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
4 Phenobarbital (PB) elicited a 3-fold increase in CYP2A5 expression (catalytic activity and mRNA), while the cAMP and protein kinase A (PKA) stimulators dibutyryl-cAMP, forskolin and Sp-cAMPs caused up to 18-fold increases in the amount of CYP2A5 mRNA. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus