Pub. Date : 2001 Feb
PMID : 11156818
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Increased dopamine d(2) receptor occupancy and elevated prolactin level associated with addition of haloperidol to clozapine. | Clozapine | prolactin | Homo sapiens |
2 | CONCLUSIONS: Adding a modest dose of haloperidol to clozapine results in the high D(2) receptor occupancy and sustained prolactin elevation usually associated with typical antipsychotics. | Clozapine | prolactin | Homo sapiens |
3 | These findings suggest that the lack of prolactin elevation associated with clozapine derives mainly from low D(2) receptor occupancy and not from the medication"s effects on other receptors. | Clozapine | prolactin | Homo sapiens |