Title : Increased dopamine d(2) receptor occupancy and elevated prolactin level associated with addition of haloperidol to clozapine.

Pub. Date : 2001 Feb

PMID : 11156818






3 Functional Relationships(s)
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1 Increased dopamine d(2) receptor occupancy and elevated prolactin level associated with addition of haloperidol to clozapine. Clozapine prolactin Homo sapiens
2 CONCLUSIONS: Adding a modest dose of haloperidol to clozapine results in the high D(2) receptor occupancy and sustained prolactin elevation usually associated with typical antipsychotics. Clozapine prolactin Homo sapiens
3 These findings suggest that the lack of prolactin elevation associated with clozapine derives mainly from low D(2) receptor occupancy and not from the medication"s effects on other receptors. Clozapine prolactin Homo sapiens