Title : Prostaglandin E2 suppressed IL-15-mediated human NK cell function through down-regulation of common gamma-chain.

Pub. Date : 2001 Jan 15

PMID : 11145664






2 Functional Relationships(s)
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1 This study was performed to investigate the suppressive effects of PGE(2) on IL-15-activated human NK cell function. Prostaglandins E interleukin 15 Homo sapiens
2 These results suggest that down-regulation of surface expression of gamma(c)-chain on NK cells may be one mechanism through which PGE(2) mediates suppression of IL-15-activated NK cell function. Prostaglandins E interleukin 15 Homo sapiens