Pub. Date : 2001 Jun
PMID : 11137534
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A one-day treatment with OA induced accumulation of the 85kDa poly(ADP-ribose) polymerase (PARP) fragment in cell lysates but the response was prevented if cells were treated with OA in the presence of the caspase inhibitors Z-VAD-FMK and Z-DEVD-FMK. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | caspase 2 | Homo sapiens |
| 2 | The possible interference of caspase inhibitors on cell death was also evaluated, and we found that both Z-VAD-FMK and Z-DEVD-FMK could contribute different extents of protection of MCF-7 and HeLa cells from toxic effects caused by OA. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | caspase 2 | Homo sapiens |