Title : Hypersulfated low molecular weight heparin with reduced affinity for antithrombin acts as an anticoagulant by inhibiting intrinsic tenase and prothrombinase.

Pub. Date : 2001 Mar 30

PMID : 11134031






2 Functional Relationships(s)
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1 Although chemical modification of LMWH, to lower its affinity for antithrombin (LA-LMWH) has no effect on its ability to inhibit intrinsic tenase, N-desulfation of LMWH reduces its activity 12-fold. Heparin, Low-Molecular-Weight serpin family C member 1 Homo sapiens
2 Although chemical modification of LMWH, to lower its affinity for antithrombin (LA-LMWH) has no effect on its ability to inhibit intrinsic tenase, N-desulfation of LMWH reduces its activity 12-fold. Heparin, Low-Molecular-Weight serpin family C member 1 Homo sapiens