Pub. Date : 2000 Dec 4
PMID : 11104854
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A preliminary study of dehydroepiandrosterone response to low-dose ACTH in chronic fatigue syndrome and in healthy subjects. | Dehydroepiandrosterone | proopiomelanocortin | Homo sapiens |
| 2 | Adrenocorticotropin (ACTH) is the primary stimulant of DHEA, and cortisol, from the adrenal. | Dehydroepiandrosterone | proopiomelanocortin | Homo sapiens |
| 3 | We chose to examine the DHEA and DHEA/cortisol response to the novel low-dose ACTH test in healthy subjects and a cohort with chronic fatigue syndrome (CFS): this test is useful in assessing subtle irregularities of pituitary-adrenal activity. | Dehydroepiandrosterone | proopiomelanocortin | Homo sapiens |
| 4 | We chose to examine the DHEA and DHEA/cortisol response to the novel low-dose ACTH test in healthy subjects and a cohort with chronic fatigue syndrome (CFS): this test is useful in assessing subtle irregularities of pituitary-adrenal activity. | Dehydroepiandrosterone | proopiomelanocortin | Homo sapiens |
| 5 | We demonstrated that 1 microg ACTH significantly elevates DHEA levels, with no difference in output between CFS and healthy subjects. | Dehydroepiandrosterone | proopiomelanocortin | Homo sapiens |
| 6 | The DHEA/cortisol ratio decreased in response to ACTH stimulation in healthy subjects but not in the CFS cohort. | Dehydroepiandrosterone | proopiomelanocortin | Homo sapiens |