Title : Aromatic hydrocarbon receptor (AhR).AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells.

Pub. Date : 2001 Feb 16

PMID : 11096091






1 Functional Relationships(s)
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1 The ability of the anticancer drug and potent genotoxic agent daunorubicin to induce mdr1 independently of AhR.Arnt further supports the proposition that mdr1 is transcriptionally up-regulated by p53 in response to DNA damage. Daunorubicin transformation related protein 53, pseudogene Mus musculus