Title : Expression and regulation of hepatic drug and bile acid transporters.

Pub. Date : 2000 Nov 16

PMID : 11090958






2 Functional Relationships(s)
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1 Indeed, biliary elimination of anionic compounds, including glutathione S-conjugates, is mediated by MRP2, whereas bile salts are excreted by a bile salt export pump (BSEP) and Class I-P-glycoprotein (P-gp) is involved in the secretion of amphiphilic cationic drugs, whereas class II-P-gp is a phospholipid transporter. Glutathione phosphoglycolate phosphatase Homo sapiens
2 Indeed, biliary elimination of anionic compounds, including glutathione S-conjugates, is mediated by MRP2, whereas bile salts are excreted by a bile salt export pump (BSEP) and Class I-P-glycoprotein (P-gp) is involved in the secretion of amphiphilic cationic drugs, whereas class II-P-gp is a phospholipid transporter. Glutathione phosphoglycolate phosphatase Homo sapiens