Title : Development of tachyphylaxis among patients taking HMG CoA reductase inhibitors.

Pub. Date : 2000 Nov 15

PMID : 11074211






1 Functional Relationships(s)
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1 The purpose of this study was to determine if long-term use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (atorvastatin, fluvastatin, lovastatin, pravastatin, or simvastatin) resulted in tachyphylaxis (a decreasing response to a physiologically active agent). Atorvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens