Pub. Date : 2000 Sep
PMID : 11071123
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of protein kinase C and phospholipase C inhibitors on IgE-dependent and IgE-independent basophil histamine release. | Histamine | proline rich transmembrane protein 2 | Homo sapiens |
| 2 | After incubation with PKC and PLC inhibitors, the stimuli were added and histamine release was measured by an automated fluorometric method. | Histamine | proline rich transmembrane protein 2 | Homo sapiens |
| 3 | CONCLUSION: These results suggest that a prodegranulatory role of PKC in basophil histamine release induced by anti-IgE, FMLP, IL-3 and GM-CSF is unlikely; conversely, it is conceivable that PLC has a role in signal transduction and histamine release induced by the above stimuli. | Histamine | proline rich transmembrane protein 2 | Homo sapiens |