Title : Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages.

Pub. Date : 2000 Nov 2

PMID : 11063620






1 Functional Relationships(s)
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1 The selected oleanane triterpenoid, CDDO (26), was found to be a potent, multifunctional agent in various in vitro assays and to show antiinflammatory activity against thioglycollate-interferon-gamma-induced mouse peritonitis. 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid interferon gamma Mus musculus