Title : SH2-B and SIRP: JAK2 binding proteins that modulate the actions of growth hormone.

Pub. Date : 2000

PMID : 11036942






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the intervening six years, a variety of signaling molecules have been identified that are tyrosyl phosphorylated in response to GH, presumably by the activated JAK2. cyclo(tyrosyl-tyrosyl) growth hormone 1 Homo sapiens
2 GH-induced binding of SH2-B to JAK2 via this site potently activates JAK2, leading to enhanced tyrosyl phosphorylation of Stat proteins and other cellular proteins. cyclo(tyrosyl-tyrosyl) growth hormone 1 Homo sapiens