Title : Cathepsin-B fusion proteins misroute secretory protein partners such as the proprotein convertase PC2-7B2 complex toward the lysosomal degradation pathways.

Pub. Date : 2000 Sep 24

PMID : 11027518






1 Functional Relationships(s)
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1 It was partially reversed by NH(4)Cl, the cell-permeable CB inhibitor CA-074Me, but not by the proteasome inhibitor Lactacystin, suggesting the potential participation of the lysosomal/endosomal degradative pathway in this process. Ammonium Chloride cathepsin B Homo sapiens