Title : Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly.

Pub. Date : 2000 Dec 22

PMID : 11007780






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The superoxide (O(2))-generating NADPH oxidase complex of phagocytes consists of a membrane-associated flavocytochrome (cytochrome b(559)) and four cytosolic proteins, p47(phox), p67(phox), p40(phox), and the small GTPase Rac (Rac1 or -2). Superoxides mitochondrially encoded cytochrome b Homo sapiens
2 The superoxide (O(2))-generating NADPH oxidase complex of phagocytes consists of a membrane-associated flavocytochrome (cytochrome b(559)) and four cytosolic proteins, p47(phox), p67(phox), p40(phox), and the small GTPase Rac (Rac1 or -2). Superoxides mitochondrially encoded cytochrome b Homo sapiens
3 NADPH oxidase activation (O(2) production) is elicited as the consequence of assembly of some or all cytosolic components with cytochrome b(559). Superoxides mitochondrially encoded cytochrome b Homo sapiens