Pub. Date : 2000 Oct
PMID : 11007759
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It has been reported that BCR-mediated signaling in B-1 cells is negatively regulated by signals from CD22, CD5 and CD72 co-receptors, and that Lyn kinase plays a crucial role in tyrosine phosphorylation of immunoreceptor tyrosine-based inhibitory motifs on the CD22 and CD72, which recruits SHP-1 to the BCR complex. | Tyrosine | signal-regulatory protein alpha | Mus musculus |
| 2 | It has been reported that BCR-mediated signaling in B-1 cells is negatively regulated by signals from CD22, CD5 and CD72 co-receptors, and that Lyn kinase plays a crucial role in tyrosine phosphorylation of immunoreceptor tyrosine-based inhibitory motifs on the CD22 and CD72, which recruits SHP-1 to the BCR complex. | Tyrosine | signal-regulatory protein alpha | Mus musculus |
| 3 | We found that Lyn kinase is also essential for the tyrosine phosphorylation of CD5 and subsequent recruitment of SHP-1 in B-1 cells upon cross-linking of BCR. | Tyrosine | signal-regulatory protein alpha | Mus musculus |
| 4 | Ly49 was rapidly tyrosine phosphorylated upon cross-linking of BCR and SHP-1 was found to recruit to the phosphorylated Ly49. | Tyrosine | signal-regulatory protein alpha | Mus musculus |