Title : Phenotypic diversity and testosterone-induced normalization of mutant L712F androgen receptor function in a kindred with androgen insensitivity.

Pub. Date : 2000 Sep

PMID : 10999816






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phenotypic diversity and testosterone-induced normalization of mutant L712F androgen receptor function in a kindred with androgen insensitivity. Testosterone androgen receptor Homo sapiens
2 In trans-activation assays, the mutant 712F-AR showed considerable deficiency at low concentrations of testosterone (0.01-0.1 nmol/L) or dihydrotestosterone (0.01 nmol/L). Testosterone androgen receptor Homo sapiens
3 Hence, the 712F-AR could switch its function from subnormal to normal within the physiological concentration range of testosterone. Testosterone androgen receptor Homo sapiens