Title : Agonistic effects of the opioid buprenorphine on the nociceptin/OFQ receptor.

Pub. Date : 2000 Jul

PMID : 10998549






2 Functional Relationships(s)
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1 Recently, we have identified buprenorphine as a full ORL1 agonist using a reporter gene assay. Buprenorphine opioid related nociceptin receptor 1 Homo sapiens
2 For further functional analysis, buprenorphine"s effects on ORL1 receptors were investigated using a K(+) channel (GIRK1) assay in Xenopus oocytes and GTPgammaS assay in CHO-K1 membrane preparations. Buprenorphine opioid related nociceptin receptor 1 Homo sapiens