Title : Ataxin-3 is translocated into the nucleus for the formation of intranuclear inclusions in normal and Machado-Joseph disease brains.

Pub. Date : 2000 Oct

PMID : 10993685






1 Functional Relationships(s)
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1 These results were confirmed in the same inclusions by double immunofluorescent staining, suggesting that expanded ataxin-3 forms a core, thereby recruiting wild-type ataxin-3 into the nucleus around the core portion, and then followed by activation of the ubiquitin/ATP-dependent pathway. Adenosine Triphosphate ataxin 3 Homo sapiens