Pub. Date : 2000 Aug 24
PMID : 10985387
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It was reported recently that nicotinic acid adenine dinucleotide phosphate (NAADP) releases Ca2+ from mammalian brain microsomes [5] and triggers Ca2+ signals in pancreatic acinar cells, where it is proposed to mediate CCK-evoked Ca2+ signals [6]. | NAADP | cholecystokinin | Homo sapiens |
| 2 | It was reported recently that nicotinic acid adenine dinucleotide phosphate (NAADP) releases Ca2+ from mammalian brain microsomes [5] and triggers Ca2+ signals in pancreatic acinar cells, where it is proposed to mediate CCK-evoked Ca2+ signals [6]. | NAADP | cholecystokinin | Homo sapiens |
| 3 | Picomolar concentrations of bombesin and CCK evoked similar patterns of cytosolic Ca2+ oscillations, but high, desensitising, NAADP concentrations selectively inhibited CCK, but not bombesin-evoked signals. | NAADP | cholecystokinin | Homo sapiens |
| 4 | We further tested whether NAADP is involved in Ca2+ signals triggered by activation of the low-affinity CCK receptor sites. | NAADP | cholecystokinin | Homo sapiens |