Title : Modification by arachidonic acid of extracellular adenosine metabolism and neuromodulatory action in the rat hippocampus.

Pub. Date : 2000 Dec 1

PMID : 10978314






1 Functional Relationships(s)
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1 The ecto-5"-nucleotidase inhibitor, alpha,beta-methylene ADP (100 microm), caused a larger inhibition (54%) of adenosine release in the presence of AA (30 microm) compared with control (37% inhibition) indicating that the AA-induced extracellular adenosine accumulation is mostly originated from an increased release and extracellular catabolism of ATP. alpha,beta-methyleneadenosine 5'-diphosphate 5' nucleotidase, ecto Rattus norvegicus