Title : Inhibition of neutrophil activation by ranitidine contributes to prevent stress-induced gastric mucosal injury in rats.

Pub. Date : 2000 Aug

PMID : 10966262






1 Functional Relationships(s)
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1 MEASUREMENTS AND MAIN RESULTS: Ranitidine inhibited the release of neutrophil elastase as well as the production of O2-, the increase in the concentrations of intracellular calcium, a second messenger of neutrophil activation, and increases in CD11b and CD18 expression, in activated neutrophils. Ranitidine elastase, neutrophil expressed Rattus norvegicus