Title : Inhibition of basophil histamine release by tyrosine kinase and phosphatidylinositol 3-kinase inhibitors.

Pub. Date : 2000 Oct

PMID : 10963852






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Among the TK inhibitors, lavendustin A exerted the most potent activity, followed by AG-126 and genistein. lavendustin A TXK tyrosine kinase Homo sapiens
2 The combined effects of lavendustin A and wortmannin were less than additive, suggesting that TK and PI3-K are involved in the same activation pathway in human basophils. lavendustin A TXK tyrosine kinase Homo sapiens