Pub. Date : 2000 Nov 17
PMID : 10958792
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 2 | In the present study, we examined the potential role of ERK1/2 activation in regulation of the p53 response to cisplatin. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 3 | Furthermore, PD98059 decreased the phosphorylation of p53 at serine 15 during cisplatin exposure, suggesting that ERK1/2 mediates in part phosphorylation of p53 during the cisplatin DNA response. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 4 | Furthermore, PD98059 decreased the phosphorylation of p53 at serine 15 during cisplatin exposure, suggesting that ERK1/2 mediates in part phosphorylation of p53 during the cisplatin DNA response. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 5 | Furthermore, PD98059 decreased the phosphorylation of p53 at serine 15 during cisplatin exposure, suggesting that ERK1/2 mediates in part phosphorylation of p53 during the cisplatin DNA response. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 6 | Furthermore, PD98059 decreased the phosphorylation of p53 at serine 15 during cisplatin exposure, suggesting that ERK1/2 mediates in part phosphorylation of p53 during the cisplatin DNA response. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 7 | These results strongly suggest that cisplatin-induced ERK activation is an up-stream regulator of the p53 response to DNA damage caused by cisplatin. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 8 | These results strongly suggest that cisplatin-induced ERK activation is an up-stream regulator of the p53 response to DNA damage caused by cisplatin. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |