Title : Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8.

Pub. Date : 2000 Sep 1

PMID : 10947972






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The S(1) subsite, the major specificity-determining site of the caspases, demonstrates tremendous selectivity, with a 20000-fold preference for cleaving substrates containing aspartic acid over glutamic acid at this position. Aspartic Acid caspase 1 Homo sapiens