Title : Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases.

Pub. Date : 2000 Aug 1

PMID : 10945608






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Under nonstressed conditions, increased expression of GSTp via a tet-off-inducible GSTp in NIH 3T3 cells increased the phosphorylation of mitogen-activated protein (MAP) kinase kinase 4, p38, extracellular receptor kinase (ERK), and inhibitor of kappa-kinase (IKK), and reduced phosphorylation of MAP kinase kinase 7 and Jun NH2-terminal kinase (JNK). tetramethylenedisulfotetramine mitogen-activated protein kinase 1 Mus musculus
2 Under nonstressed conditions, increased expression of GSTp via a tet-off-inducible GSTp in NIH 3T3 cells increased the phosphorylation of mitogen-activated protein (MAP) kinase kinase 4, p38, extracellular receptor kinase (ERK), and inhibitor of kappa-kinase (IKK), and reduced phosphorylation of MAP kinase kinase 7 and Jun NH2-terminal kinase (JNK). tetramethylenedisulfotetramine mitogen-activated protein kinase 1 Mus musculus