Pub. Date : 2000 Aug 25
PMID : 10942596
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment of proliferating granulosa cells with 30 microM progesterone, which induces a reversible phenocopy of the cholesterol trafficking defect of Niemann-Pick type C disease, increased NPC1 mRNA levels threefold. | Progesterone | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 2 | The protein synthesis inhibitor, cycloheximide, also increased NPC1 mRNA levels, augmenting the progesterone-induced increase in NPC1 mRNA abundance. | Progesterone | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 3 | The protein synthesis inhibitor, cycloheximide, also increased NPC1 mRNA levels, augmenting the progesterone-induced increase in NPC1 mRNA abundance. | Progesterone | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 4 | All of the cysteine-rich loop mutants were localized to cholesterol-engorged lysosomes in a pattern mimicking the distribution of NPC1 in progesterone-treated cells. | Progesterone | NPC intracellular cholesterol transporter 1 | Homo sapiens |