Title : Combination of interferon alpha with either Ara-C or ATRA in vitro reduces the selective action of interferon against CML CFU-GM.

Pub. Date : 2000 Aug

PMID : 10942234






3 Functional Relationships(s)
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1 However, addition of ATRA to cultures containing IFN-alpha reversed the selective inhibition of CML CFU-GM replating seen in cultures containing IFN-alpha alone. Tretinoin interferon alpha 1 Homo sapiens
2 However, addition of ATRA to cultures containing IFN-alpha reversed the selective inhibition of CML CFU-GM replating seen in cultures containing IFN-alpha alone. Tretinoin interferon alpha 1 Homo sapiens
3 Thus we conclude that combining IFN-alpha with Ara-C or ATRA neutralises the effect of IFN-alpha on CML CFU-GM. Tretinoin interferon alpha 1 Homo sapiens