Pub. Date : 2000 Aug
PMID : 10935541
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Similarly, antiandrogenic ligands, cyproterone acetate and casodex, were also capable of translocating the cytoplasmic AR into the nucleus albeit at a slower rate than the androgen 5alpha-dihydrotestosterone (DHT). | Dihydrotestosterone | androgen receptor | Rattus norvegicus |
2 | Subsequent exposure of the casodex-treated cell to DHT rapidly (15-30 min) altered the homogeneous to punctate distribution of the already translocated nuclear AR. | Dihydrotestosterone | androgen receptor | Rattus norvegicus |
3 | When transported into the nucleus either by casodex or by DHT, GFP-AR was resistant to 2 M NaCl extraction, indicating that the homogeneously distributed AR is also associated with the nuclear matrix. | Dihydrotestosterone | androgen receptor | Rattus norvegicus |