Title : Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize follicular fluid meiosis activating sterol.

Pub. Date : 2000 Aug

PMID : 10927636






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CYP51 in the presence of NADPH-cytochrome P450 reductase converts lanosterol to follicular fluid meiosis activating sterol (FF-MAS), an intermediate of cholesterol biosynthesis which accumulates in gonads and has an additional function as oocyte meiosis-activating substance. Sterols cytochrome P450, family 51 Rattus norvegicus