Title : Indirect inhibition of mitochondrial dihydroorotate dehydrogenase activity by nitric oxide.

Pub. Date : 2000 Apr 15

PMID : 10889450






1 Functional Relationships(s)
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1 Since orotate is the precursor of all pyrimidine nucleotides, indirect inhibition of DHODH by NO may significantly contribute to NO-dependent cytotoxicity. Pyrimidine Nucleotides dihydroorotate dehydrogenase (quinone) Homo sapiens