Title : Brain-targeted chemical delivery of [Leu2, Pip3]-TRH: synthesis and biological evaluation.

Pub. Date : 2000 May

PMID : 10882017






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Sequential metabolism of the obtained "packaged" chemical delivery system, (CDS), DHT-Pro-Pro-Gln-Leu-Pip-OCh, should yield a "locked-in" precursor following the oxidative conversion of the dihydrotrigonellyl (DHT) to the trigonellyl (T+) moiety, followed by removal of the cholesteryl function and cleavage of the T+-Pro-Pro by prolyl endopeptidase. Dihydrotestosterone prolactin induced protein Homo sapiens