Title : Testosterone suppresses the response of the hypothalamic-pituitary-adrenal axis to interleukin-6.

Pub. Date : 2000

PMID : 10859487






2 Functional Relationships(s)
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1 The release of both ACTH and corticosterone was significantly attenuated in the intact (n = 9) and testosterone-replaced (n = 5) animals compared to the castrated animals without replacement (n = 7). Testosterone proopiomelanocortin Homo sapiens
2 Peak ACTH levels were 340 +/- 58 and 133 +/- 41 pg/ml in the intact and testosterone-replaced animals versus 678 +/- 170 pg/ml in the castrated animals (p < 0.02). Testosterone proopiomelanocortin Homo sapiens