Pub. Date : 2000 May
PMID : 10857764
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The role of ceramide in the modulation of intracellular Ca2+ levels by interleukin 1 beta in rat cortical synaptosomes. | Ceramides | interleukin 1 beta | Rattus norvegicus |
| 2 | We now report that the effects of IL-1beta on [Ca2+]i are mimicked by the sphingolipid metabolite ceramide. | Ceramides | interleukin 1 beta | Rattus norvegicus |
| 3 | In cortical synaptosomes ceramide elevates [Ca2+]i in a p42 MAP kinase-dependent manner, and we conclude that the effects of IL-1beta on Ca2+ homeostasis involve ceramide as an upstream component of the p42 MAP kinase pathway. | Ceramides | interleukin 1 beta | Rattus norvegicus |