Title : Effects of the immunosuppressant FK506 on intracellular Ca2+ release and Ca2+ accumulation mechanisms.

Pub. Date : 2000 Jun 15

PMID : 10856121






1 Functional Relationships(s)
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1 In conclusion, FK506 inhibited active Ca2+ uptake by the SERCA Ca2+ pump; in addition, FK506 enhanced intracellular Ca2+ release through the RyR, but it had no direct effect on IP3-induced Ca2+ release. Tacrolimus ryanodine receptor 1 Homo sapiens