Title : Marked increase of venlafaxine enantiomer concentrations as a consequence of metabolic interactions: a case report.

Pub. Date : 2000 May

PMID : 10855463






1 Functional Relationships(s)
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1 At the second blood sampling, after addition of thioridazine (260 mg/day), which is a strong CYP2D6 inhibitor, concentrations of venlafaxine were further increased (2.76 mg/l), and concentrations of O-desmethylvenlafaxine decreased (0.22 mg/l). Thioridazine cytochrome P450 family 2 subfamily D member 6 Homo sapiens