Title : Sterol methyltransferase 1 controls the level of cholesterol in plants.

Pub. Date : 2000 Jun

PMID : 10852933






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 smt1 has an altered sterol content: it accumulates cholesterol and has less C-24 alkylated sterols content. Sterols sterol methyltransferase 1 Arabidopsis thaliana
2 smt1 has an altered sterol content: it accumulates cholesterol and has less C-24 alkylated sterols content. Sterols sterol methyltransferase 1 Arabidopsis thaliana
3 Escherichia coli extracts, obtained from a strain expressing the Arabidopsis SMT1 protein, can perform both the methyl and ethyl additions to appropriate sterol substrates, although with different kinetics. Sterols sterol methyltransferase 1 Arabidopsis thaliana
4 The fact that smt1 null mutants still produce alkylated sterols and that SMT1 can catalyze both alkylation steps shows that there is considerable overlap in the substrate specificity of enzymes in sterol biosynthesis. Sterols sterol methyltransferase 1 Arabidopsis thaliana
5 The fact that smt1 null mutants still produce alkylated sterols and that SMT1 can catalyze both alkylation steps shows that there is considerable overlap in the substrate specificity of enzymes in sterol biosynthesis. Sterols sterol methyltransferase 1 Arabidopsis thaliana
6 The availability of the SMT1 gene and mutant should permit the manipulation of phytosterol composition, which will help elucidate the role of sterols in animal nutrition. Sterols sterol methyltransferase 1 Arabidopsis thaliana