Title : Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate.

Pub. Date : 2000 Jun

PMID : 10842159






1 Functional Relationships(s)
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1 The transfer of the iNOS gene activated the p42/44 MAPK, and inhibition of this MAPK pathway with PD98059 partially blocked the antiproliferative effects of NO and completely inhibited the p21 stimulatory effects of NO. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one H3 histone pseudogene 16 Homo sapiens