Title : Dietary docosahexaenoic acid but not eicosapentaenoic acid suppresses lipopolysaccharide-induced interleukin-1 beta mRNA induction in mouse spleen leukocytes.

Pub. Date : 2000 Mar

PMID : 10841036






3 Functional Relationships(s)
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1 Dietary docosahexaenoic acid but not eicosapentaenoic acid suppresses lipopolysaccharide-induced interleukin-1 beta mRNA induction in mouse spleen leukocytes. Docosahexaenoic Acids interleukin 1 beta Mus musculus
2 IL-1beta mRNA induction upon lipopolysaccharide (LPS) stimulation in spleen leukocytes in the DHA diet group was significantly lower than in the BT diet group, but the EPA diet was without any significant effect. Docosahexaenoic Acids interleukin 1 beta Mus musculus
3 Thus, dietary EPA and DHA inhibited arachidonate metabolism similarly but had different effects on IL-1beta mRNA induction in mouse spleen leukocytes. Docosahexaenoic Acids interleukin 1 beta Mus musculus