Title : Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions.

Pub. Date : 2000 Apr

PMID : 10826498






2 Functional Relationships(s)
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Protein Name
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1 A decreased ratio can relieve the inhibition of PDH as shown by the transfer of acetyl groups from acetyl-CoA to carnitine, forming acetylcarnitine, a reaction catalyzed by carnitine acetyl-transferase. Carnitine pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens
2 The actions of L-carnitine and propionyl-L-carnitine cannot be explained as exclusively dependent on the stimulation of fatty acid oxidation but rather on a marked increase in glucose oxidation, via a relief of PDH inhibition caused by the elevated acetyl-CoA/CoA ratio. Carnitine pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens