Pub. Date : 2000 May
PMID : 10812248
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: When added at day 0, calcitriol blocked DC differentiation from monocytes and inhibited the generation of CD1a(+) cells from progenitor cells while increasing CD14(+) cells. | Calcitriol | CD1a molecule | Homo sapiens |
| 2 | Exposure of immature DCs to calcitriol at day 6 resulted in a loss of the DC-characteristic surface molecule CD1a, downregulation of the costimulatory molecules CD40 and CD80, and MHC class II expression, whereas the monocyte/macrophage marker CD14 was clearly reinduced. | Calcitriol | CD1a molecule | Homo sapiens |
| 3 | In contrast, the mature CD83(+) DCs remained CD1a(+)CD14(-) when exposed to calcitriol. | Calcitriol | CD1a molecule | Homo sapiens |