Title : Evidence for the catalysis of dextromethorphan O-demethylation by a CYP2D6-like enzyme in pig liver.

Pub. Date : 2000 Jun

PMID : 10806376






1 Functional Relationships(s)
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1 The reaction was sensitive to inhibition by the CYP2D6-selective inhibitors quinidine, quinine, lobeline and norfluoxetine, whereas chemical inhibitors selective for other CYP isoforms failed to affect the reaction. Quinine cytochrome P450 family 2 subfamily D member 6 Sus scrofa