Title : Cleavage of Bax-alpha and Bcl-x(L) during carboplatin-mediated apoptosis in squamous cell carcinoma cell line.

Pub. Date : 2000 May

PMID : 10793331






1 Functional Relationships(s)
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1 The pretreatment of cells with pan-caspase inhibitor Z-VAD-fmk markedly prevented CBDCA-mediated cytotoxicity/apoptosis and the modulation of Bcl-2 family proteins (generation of p18 Bax-alpha and p16 Bcl-x(L) ) with only slight prevention of decline of Deltapsi(m). benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone H3 histone pseudogene 12 Homo sapiens