Title : Aspartate 351 of estrogen receptor alpha is not crucial for the antagonist activity of antiestrogens.

Pub. Date : 2000 Jul 7

PMID : 10787412






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Aspartate 351 of estrogen receptor alpha is not crucial for the antagonist activity of antiestrogens. Aspartic Acid estrogen receptor 1 Homo sapiens
2 This stabilizing role of Asp-351 could be due to interaction of Asp-351 with the amide group of the peptide bond between Leu-539 and Leu-540 in helix 12 observed in the active conformation of the ERalpha ligand binding domain. Aspartic Acid estrogen receptor 1 Homo sapiens
3 This stabilizing role of Asp-351 could be due to interaction of Asp-351 with the amide group of the peptide bond between Leu-539 and Leu-540 in helix 12 observed in the active conformation of the ERalpha ligand binding domain. Aspartic Acid estrogen receptor 1 Homo sapiens